While the plague ravages Seville, Mateo and Valerio find the missing Carmen Galvez, lover of the deceased merchant killed.She informs them that behind the murders is Ledesma, secret leader of the Sevillian Protestants. Zuniga is appointed a member of the Cabildo to replace Morata and tries by all means to get them to open the port of the city. In the silk factory several workers try to rape Eugenia and Teresa decides to dismiss all those who have participated in the matter. To replace them, he hires several prostitutes chosen by Eugenia. Days later, Teresa is assaulted and humiliated with violence. Another corpse appears, it is Dresdner, treasurer of the Casa de la Moneda and economic support of Zuniga. This murder is similar to the previous ones and points in the same direction: Ledesma. Leandra, Valerio's girlfriend, sick with plague.